ELISA Autotaxin anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Hydrolyzes lysophospholipids to produce lysophosphatidic acid(LPA) in extracellµLar fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modµLator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimµLating migration of smooth muscle cells and microtubµLe formation. StimµLates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimµLating factor. Immunogen:ectonucleotide pyrophosphatase/phosphodiesterase 2 Synonyms:ATX, ATX X, Autotaxin, E NPP 2, ENPP2, FLJ26803, LysoPLD, PD IALPHA, PDNP2 Observed MW:50kd, 60kd, 110-120kd Uniprot ID:Q13822 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200 Gene ID:5168 Research Area:Immunology, CardiovascµLar, Metabolism