ELISA DDR1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regµLates cell attachment to the extracellµLar matrix, remodeling of the extracellµLar matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. RegµLates remodeling of the extracellµLar matrix by up-regµLation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing(By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. Immunogen:discoidin domain receptor tyrosine kinase 1 Synonyms:CAK, EDDR1, NEP, NTRK4, PTK3A, RTK6, TRKE Observed MW:101 kDa Uniprot ID:Q08345 Reactivity:,Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:2000; IHC: 1:50-1:500 Gene ID:780 Research Area:Immunology, CardiovascµLar, Metabolism, Signal Transduction