ELISA CLASP2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:MicrotubµLe plus-end tracking protein that promotes the stabilization of dynamic microtubµLes(PubMed:26003921). Involved in the nucleation of noncentrosomal microtubµLes originating from the trans-Golgi network(TGN). Required for the polarization of the cytoplasmic microtubµLe arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubµLes by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2(PubMed:16824950). This cortical microtubµLe stabilizing activity is regµLated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle(PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2-dependent stabilization of microtubµLes at the cell cortex. Immunogen:cytoplasmic linker associated protein 2 Synonyms:KIAA0627 Observed MW:140-160 kDa Uniprot ID:O75122 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:2000 Gene ID:23122 Research Area:Cell Division and Proliferation