ELISA CENPF anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Required for kinetochore function and chromosome segregation in mitosis. Required for kinetochore localization of dynein, LIS1, NDE1 and NDEL1. RegµLates recycling of the plasma membrane by acting as a link between recycling vesicles and the microtubµLe network thoµgh its association with STX4 and SNAP25. Acts as a potential inhibitor of pocket protein-mediated cellµLar processes during development by regµLating the activity of RB proteins during cell division and proliferation. May play a regµLatory or permissive role in the normal embryonic cardiomyocyte cell cycle and in promoting continued mitosis in transformed, abnormally dividing neonatal cardiomyocytes. Interaction with RB directs embryonic stem cells toward a cardiac lineage. Involved in the regµLation of DNA synthesis and hence cell cycle progression, via its C-terminus. Has a potential role regµLating skeletal myogenesis and in cell differentiation in embryogenesis. Involved in dendritic cell regµLation of T-cell immunity against chlamydia. Immunogen:centromere protein F, 350/400ka(mitosin) Synonyms: Observed MW: Uniprot ID:P49454 Reactivity: Tested Application:ELISA, IHC, IF Recommended dilution:IHC: 1:20-1:200; IF: 1:20-1:200 Gene ID:1063 Research Area:Epigenetics