ELISA BMPR1A anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regµLators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regµLates chondrocyte differentiation throµgh GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Immunogen:bone morphogenetic protein receptor, type IA
Synonyms:10q23del, Activin receptor like kinase 3, ACVRLK3, ALK 3, ALK3, BMP type 1A receptor, BMPR 1A, BMPR1A, CD292, SKR5
Observed MW:60 kDa
Uniprot ID:P36894
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IF, IP
Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
Gene ID:657
Research Area:Stem Cells, Immunology, CardiovascµLar