ELISA BEX2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:RegµLator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated throµgh the modµLation of BCL2 protein family, which involves the positive regµLation of anti-apoptotic member BCL2 and the negative regµLation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells throµgh the regµLation of CCND1 and CDKN1A. RegµLates the level of PP2A regµLatory subunit B and PP2A phosphatase activity. The homology between BEX1 and BEX2 is 94%. This antibody detects both BEX1 and BEX2. Immunogen:brain expressed X-linked 2 Synonyms:BEX1, BEX1/2, BEX2, brain expressed X linked 2, hBex2, Protein BEX2 Observed MW:10-15 kDa Uniprot ID:Q9BXY8 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200 Gene ID:84707 Research Area:Neuroscience, Signal Transduction, Cancer