ELISA BCOR anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and mLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regµLator of osteo-dentiogenic capacity in adµLt stem cells; the function implies inhibition of methylation on histone H3 'Lys-4'(H3K4me3) and 'Lys-36'(H3K36me2). Immunogen:BCL6 co-repressor Synonyms:KIAA1575 Observed MW:186 kDa Uniprot ID:Q6W2J9 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500 - 1:2000 Gene ID:54880 Research Area:Metabolism