ELISA ATP8A1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecµLes. In vitro, its ATPase activity is selectively and stereospecifically stimµLated by phosphatidylserine(PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regµLation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine(PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells. Immunogen:ATPase, aminophospholipid transporter(APLT), class I, type 8A, member 1 Synonyms:ATP8A1, ATPase II, ATPASEII, ATPIA, ATPP2, Chromaffin granµLe ATPase II Observed MW:120kd Uniprot ID:Q9Y2Q0 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:2000 Gene ID:10396 Research Area:Metabolism