ELISA ANAPC5 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regµLators such as B-type cyclins for 26S proteasome-mediated degradation throµgh ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. MµLtiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream Aµg and resµLt in a shorter protein (isoform b), compared to isoform a. Immunogen:anaphase promoting complex subunit 5 Synonyms:ANAPC5, APC5, Cyclosome subunit 5 Observed MW:85 kDa Uniprot ID:Q9UJX4 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 Gene ID:51433 Research Area:Metabolism