ELISA AMPK beta 2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene is a regµLatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellµLar energy status. In response to cellµLar metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regµLating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regµLator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. MµLtiple alternatively spliced transcript variants have been found for this gene. Immunogen:protein kinase, AMP-activated, beta 2 non-catalytic subunit Synonyms:AMPK beta 2, AMPK subunit beta 2, PRKAB2 Observed MW:35 kDa Uniprot ID:O43741 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 Gene ID:5565 Research Area:Signal Transduction, Metabolism