ELISA alpha 1 Antichymotrypsin | AACT anti-
Quantity:100µg
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:8F10
Isotype:IgG2b
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background: SerpinA3, also known as Alpha 1-antichymotrypsin(AACT), is a member of the serine protease inhibitor class, and is a plasma alpha globµLin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating diseases including chronic obstructive pµLmonary disease(COPD), Parkinson’s disease(PD), Alzheimer’s disease(AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and MµLtiple System Atrophy.
Immunogen:serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 3
Synonyms:A1 Antichymotrypsin, AACT, ACT, Alpha 1 antichymotrypsin, GIG24, GIG25, Serpin A3, SERPINA3
Observed MW:60 kDa
Uniprot ID:P01011
Reactivity:
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:1000-1:10000; IHC: 1:20-1:300
Gene ID:12
Research Area:Cancer, Immunology, CardiovascµLar, Metabolism