ELISA ADIPOQ anti-
Quantity:100µg
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:6E1
Isotype:IgG2a
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Important adipokine involved in the control of fat metabolism and insµLin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. StimµLates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regµLating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling throµgh a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Immunogen:adiponectin, C1Q and collagen domain containing
Synonyms:ACDC, ACRP30, adiponectin, ADIPOQ, ADIPQTL1, ADPN, APM 1, APM1, GBP28, Gelatin binding protein
Observed MW:26 kDa
Uniprot ID:Q15848
Reactivity:, Mouse
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:9370
Research Area:Signal Transduction, Metabolism