ELISA ACVRL1 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regµLator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regµLators. May bind activin as well.
Immunogen:activin A receptor type II-like 1
Synonyms:Activin receptor like kinase 1, ACVRL1, ACVRLK1, ALK 1, ALK1, HHT, HHT2, ORW2, SKR3, TSR I
Observed MW:56 kDa
Uniprot ID:P37023
Reactivity:
Tested Application:ELISA, WB, IHC, FC, IP
Recommended dilution:WB: 1:200-1:1000; IHC: 1:100-1:400; IP: 1:200-1:1000
Gene ID:94
Research Area:CardiovascµLar, Metabolism, Signal Transduction