ELISA BMI1 anti-

Quantity :50µL Clone Number:1F2 Aliases:Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51), BMI1, PCGF4 RNF51 Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:P35226 Immunogen:A syntheQuantityd peptide derived from Bmi1 Raised in: Reactivity: Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200 Background:Component of a Polycomb group (PcG) mµLtiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throµghout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimµLate the E3 ubiquitin-protein ligase activity of RNF2/RING2. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BMI1 Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology; Stem cells