ELISA DDR1 anti-

Quantity :100µL Clone Number: Aliases:CAK antibody; CD 167 antibody; CD167 antibody; CD167 antigen-like family member A antibody; CD167a antibody; Cell adhesion kinase antibody; DDR 1 antibody; DDR antibody; DDR1 antibody; DDR1_ antibody; Discoidin domain receptor antibody; Discoidin domain receptor tyrosine kinase 1 antibody; Discoidin receptor tyrosine kinase antibody; Discoidin receptor tyrosine kinase isoform a antibody; EDDR 1 antibody; EDDR1 antibody; Epithelial discoidin domain receptor 1 antibody; Epithelial discoidin domain-containing receptor 1 antibody; Epithelial specific receptor kinase antibody; HGK2 antibody; Mammarian carcinoma kinase 10 antibody; Mammary carcinoma kinase 10 antibody; MCK-10 antibody; MCK10 antibody; NEP antibody; Neuroepithelial tyrosine kinase antibody; Neurotrophic tyrosine kinase receptor type 4 antibody; NTRK 4 antibody; NTRK4 antibody; OTTHUMP00000029343 antibody; OTTHUMP00000029344 antibody; OTTHUMP00000029345 antibody; OTTHUMP00000029346 antibody; OTTHUMP00000029347 antibody; OTTHUMP00000164863 antibody; OTTHUMP00000164867 antibody; OTTHUMP00000222080 antibody; Protein-tyrosine kinase 3A antibody; Protein-tyrosine kinase RTK-6 antibody; PTK 3 antibody; PTK 3A protein tyrosine kinase 3A antibody; PTK3 antibody; PTK3A antibody; Receptor tyrosine kinase NEP antibody; RTK 6 antibody; RTK6 antibody; TRK E antibody; TRKE antibody; Tyrosine kinase DDR antibody; Tyrosine kinase receptor E antibody; Tyrosine-protein kinase CAK antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q08345 Immunogen:SyntheQuantityd peptide derived from internal of DDR1. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regµLates cell attachment to the extracellµLar matrix, remodeling of the extracellµLar matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. RegµLates remodeling of the extracellµLar matrix by up-regµLation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing By similarity. Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11. di Marco E., J. Biol. Chem. 268:24290-24295(1993). Johnson J.D., Proc. Natl. Acad. Sci. U.S.A. 90:5677-5681(1993). Laval S., Cell Growth Differ. 5:1173-1183(1994). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DDR1 Research Areas:Neuroscience?Cancer?CardiovascµLar;Signal transduction