ELISA BMPR2 anti-

Quantity :50µL Clone Number: Aliases:BMP type II receptor antibody; BMP type-2 receptor antibody; BMPR 2 antibody; BMPR 3 antibody; BMPR II antibody; BMPR-2 antibody; BMPR-II antibody; Bmpr2 antibody; BMPR2_ antibody; BMPR3 antibody; BMPRII antibody; BMR 2 antibody; BMR2 antibody; Bone morphogenetic protein receptor type 2 antibody; Bone morphogenetic protein receptor type II antibody; Bone morphogenetic protein receptor type-2 antibody; Bone morphogenic protein receptor type II serine threonine kinase antibody; BRK 3 antibody; BRK3 antibody; PPH 1 antibody; PPH1 antibody; Serine threonine kinase type II activin receptor like kinase antibody; T ALK antibody; TALK antibody; Type II activin receptor like kinase antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13873 Immunogen:Fusion protein of BMPR2 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:25-1:100 Background:This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals throµgh the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pµLmonary hypertension, both familial and fenfluramine-associated, and with pµLmonary venoocclusive disease. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BMPR2 Research Areas:CardiovascµLar;Signal transduction?Stem cells