ELISA BCAS3 anti-

Quantity :50µL Clone Number: Aliases:1500019F07Rik antibody; 2610028P08Rik antibody; AU021018 antibody; BC028339 antibody; BCAS3 antibody; BCAS3_ antibody; Breast carcinoma-amplified sequence 3 antibody; FLJ20128 antibody; GAOB1 antibody; K20D4 antibody; MAAB antibody; Maab1 protein antibody; MGC4973 antibody; rudhira antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H6U6 Immunogen:Synthetic peptide of BCAS3 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:BCAS3 (breast carcinoma amplified sequence 3), also designated MAAB or GAOB1, is a 913 amino acid protein that is believed to be involved in breast cancer progression. The gene is regµLated by ER (estrogen receptor alpha) and expressed in mµLtiple tissues, including malignant brain lesions. It is overexpressed and amplified in breast cancer cell lines. BCAS3 contains three WD40 repeat regions, a bromodomain, a rare zinc-finger motif, four probable DNA-binding domains, and two kinase-inducible phosphorylation domains. Five variants are produced due to alternative splicing. BCAS3 interacts with histone H3 and PCAF, which is indicative of histone acetyltransferase activity. BCAS3 also exhibits ER transactiviation activity by acting as a coactivator with PELP1 or MTA1. The amplification and translocation between the BCAS3 gene and the BCAS4 gene resµLts in a fusion transcript is overexpressed in MCF-7 cells. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BCAS3 Research Areas:Cancer;Tags & Cell Markers;Stem cells