ELISA CFL1|CFL2 (Ab-88) anti-

Quantity :100µL Clone Number: Aliases:Cofilin; non-muscle isoform 18 kDa phosphoprotein; Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P23528/Q9Y281 Immunogen:Peptide sequence around aa. 86~90 (A-T-Y-E-T) derived from cofilin1/cofilin2. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 Background: Controls reversibly actin polymerization and depolymerization in a pH-sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods. Carlier, M. et al. (1999) J. Biol. Chem. 274, 33827-33830. Arber, S. et al. (1998) Nature 393, 805-809. Yang, N. et al. (1998) Nature 393, 809-812. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CFL1/CFL2 Research Areas:Neuroscience?Cancer?CardiovascµLar;Signal transduction