ELISA ASIC3 anti-
Quantity :50µL
Clone Number:
Aliases:ACCN 3 antibody; Accn3 antibody; ACCN3_ antibody; Acid sensing ion channel 3 antibody; Acid-sensing ion channel 3 antibody; Amiloride sensitive cation channel 3 antibody; Amiloride sensitive cation channel 3 testis antibody; Amiloride-sensitive cation channel 3 antibody; ASIC 3 antibody; ASIC3 antibody; DRASIC antibody; hASIC 3 antibody; hASIC3 antibody; hTNaC 1 antibody; hTNaC1 antibody; ModµLatory subunit of ASIC 2a antibody; ModµLatory subunit of ASIC2a antibody; Neuronal amiloride sensitive cation channel 3 antibody; Neuronal amiloride-sensitive cation channel 3 antibody; Proton gated cation channel subunit antibody; SLNAC 1 antibody; SLNAC1 antibody; Testis sodium channel 1 antibody; TNaC 1 antibody; TNaC1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9UHC3
Immunogen:Recombinant Acid-sensing ion channel 3 protein (62-320AA)
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Background:Cation channel with high affinity for sodium, which is gated by extracellµLar protons and inhibited by the diuretic amiloride. Generates a biphasic current with a fast inactivating and a slow sustained phase. In sensory neurons is proposed to mediate the pain induced by acidosis that occurs in ischemic, damaged or inflamed tissue. May be involved in hyperalgesia. May play a role in mechanoreception. Heteromeric channel assembly seems to modµLate channel properties.
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjµgate:Non-conjµgated
Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:ASIC3
Research Areas:Neuroscience