ELISA BEX2 Antibody, HRP

Quantity :50µg Clone Number: Aliases:BEX2Protein BEX2 antibody; Brain-expressed X-linked protein 2 antibody; hBex2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9BXY8 Immunogen:Recombinant Protein BEX2 protein (1-128AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:RegµLator of mitochondrial apoptosis and G1 cell cycle in breast cancer. Protects the breast cancer cells against mitochondrial apoptosis and this effect is mediated throµgh the modµLation of BCL2 protein family, which involves the positive regµLation of anti-apoptotic member BCL2 and the negative regµLation of pro-apoptotic members BAD, BAK1 and PUMA. Required for the normal cell cycle progression during G1 in breast cancer cells throµgh the regµLation of CCND1 and CDKN1A. RegµLates the level of PP2A regµLatory subunit B and PP2A phosphatase activity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BEX2 Research Areas:Others