ELISA ASL anti-

Quantity :50µL Clone Number: Aliases:Argininosuccinase antibody; Argininosuccinate lyase antibody; Arginosuccinase antibody; ARLY_ antibody; ASAL antibody; ASL antibody; EC 4.3.2.1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P04424 Immunogen:Fusion protein of ASL Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene resµLt in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ASL Research Areas:Metabolism;Signal transduction