ELISA ATG4C anti-

Quantity :50µL Clone Number: Aliases:APG4 autophagy 4 homolog C (S. cerevisiae) antibody; APG4 autophagy 4 homolog C antibody; APG4 C antibody; APG4-C antibody; APG4C antibody; ATG 4C antibody; ATG4 autophagy related 4 homolog C (S. cerevisiae) antibody; ATG4 autophagy related 4 homolog C antibody; Atg4c antibody; ATG4C_ antibody; AUT (S. cerevisiae) like 1; cysteine endopeptidase antibody; AUT like 1; cysteine endopeptidase (S. cerevisiae) antibody; AUT like 1; cysteine endopeptidase antibody; AUT like 3 cysteine endopeptidase antibody; AUT-like 3 cysteine endopeptidase antibody; AUTL1 antibody; AUTL3 antibody; Autophagin 3 antibody; Autophagin-3 antibody; Autophagy related 4C cysteine peptidase antibody; Autophagy related cysteine endopeptidase 3 antibody; Autophagy related protein 4 homolog C antibody; Autophagy-related cysteine endopeptidase 3 antibody; Autophagy-related protein 4 homolog C antibody; Cysteine protease ATG4C antibody; EC 3.4.22 antibody; FLJ14867 antibody; OTTHUMP00000010715 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96DT6 Immunogen:Recombinant Cysteine protease ATG4C protein (259-458AA) Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 Background:Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressfµL conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjµgation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjµgated forms. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ATG4C Research Areas:Cancer; CardiovascµLar; Cell biology; Metabolism; Signal transduction