ELISA BATF2 Antibody, FITC
Quantity :50µg
Clone Number:
Aliases:BATF2Basic leucine zipper transcriptional factor ATF-like 2 antibody; B-ATF-2 antibody; Suppressor of AP-1 regµLated by IFN antibody; SARI antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q8N1L9
Immunogen:Recombinant Basic leucine zipper transcriptional factor ATF-like 2 protein (1-189AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5\'-TGA[CG]TCA-3\' and regµLates expression of target genes. Selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. Possibly acts by interfering with AP-1 binding to CYR61 promoter.
Clonality:Polyclonal
Isotype:IgG
Purification Method:>95%, Protein G purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:BATF2
Research Areas:Epigenetics and Nuclear Signaling