ELISA BCOR Antibody, Biotin

Quantity :50µg Clone Number: Aliases:5830466J11Rik antibody; 8430401K06Rik antibody; ANOP 2 antibody; ANOP2 antibody; BCL 6 co repressor antibody; BCL 6 corepressor antibody; BCL 6 interacting corepressor antibody; BCL-6 corepressor antibody; BCL6 co repressor antibody; BCL6 corepressor antibody; BCL6 interacting corepressor antibody; BCoR antibody; BCOR_ antibody; FLJ20285 antibody; FLJ38041 antibody; KIAA1575 antibody; MAA 2 antibody; MAA2 antibody; MCOPS 2 antibody; MCOPS2 antibody; MGC131961 antibody; MGC71031 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q6W2J9 Immunogen:Recombinant BCL-6 corepressor protein (1569-1755AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and mLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A; impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regµLator of osteo-dentiogenic capacity in adµLt stem cells; the function implies inhibition of methylation on histone H3 \'Lys-4\' (H3K4me3) and \'Lys-36\' (H3K36me2). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BCOR Research Areas:Epigenetics and Nuclear Signaling