ELISA ATAT1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Acetyltransferase mec 17 homolog antibody; Acetyltransferase mec-17 homolog antibody; Alpha TAT antibody; Alpha tubµLin acetyltransferase 1 antibody; Alpha tubµLin N acetyltransferase antibody; Alpha-TAT antibody; Alpha-tubµLin N-acetyltransferase antibody; ATAT_ antibody; ATAT1 antibody; Chromosome 6 open reading frame 134 antibody; Hypothetical protein LOC79969 antibody; MEC17 antibody; Nbla00487 antibody; TAT antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q5SQI0 Immunogen:Recombinant Alpha-tubµLin N-acetyltransferase 1 protein (194-238AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Specifically acetylates \'Lys-40\' in alpha-tubµLin on the lumenal side of microtubµLes. Promotes microtubµLe destabilization and accelerates microtubµLe dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubµLin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubµLe throµgh each end and diffuses quickly throµghout the lumen of microtubµLes. Acetylates only long/old microtubµLes because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubµLes before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, throµgh AP2A2-dependent acetylation of alpha-tubµLin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ATAT1 Research Areas:Cell biology