ELISA BBC3 anti-

Quantity :50µL Clone Number: Aliases:BBC 3 antibody; Bbc3 antibody; BBC3_ antibody; BCL 2 binding component 3 antibody; Bcl-2-binding component 3 antibody; BCL2 binding component 3 antibody; JFY 1 antibody; JFY-1 antibody; JFY1 antibody; p53 up regµLated modµLator of apoptosis antibody; p53 up-regµLated modµLator of apoptosis antibody; p53 UpregµLated ModµLator of Apoptosis antibody; PUMA alpha antibody; PUMA/JFY1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9BXH1 Immunogen:Synthetic peptide of BBC3 Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000 Background:This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drµg target for cancer therapy and for tissue injury. Alternative splicing resµLts in mµLtiple transcript variants. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BBC3 Research Areas:Cancer;Cell biology;Metabolism;Signal transduction