ELISA CNOT7 anti-

Quantity :100µL Clone Number: Aliases:BTG1 binding factor 1 antibody; BTG1-binding factor 1 antibody; CAF 1 antibody; CAF-1 antibody; CAF1 antibody; Carbon catabolite repressor protein (CCR4) associative factor 1 antibody; CCR4 associated factor 1 antibody; CCR4 NOT transcription complex subunit 7 antibody; CCR4-associated factor 1 antibody; CCR4-NOT transcription complex subunit 7 antibody; CNOT 7 antibody; Cnot7 antibody; CNOT7_ antibody; hCAF 1 antibody; hCAF1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UIV1 Immunogen:SyntheQuantityd peptide derived from N-terminal of CNOT7. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellµLar mRNA deadenylases and is linked to various cellµLar processes including bµLk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regµLation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity. Bogdan J.A., Biochem. J. 336:471-481(1998). The MGC Project Team; Genome Res. 14:2121-2127(2004). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CNOT7 Research Areas:Epigenetics and Nuclear Signaling