ELISA ARNT anti-

Quantity :100µL Clone Number: Aliases:arnT antibody; ARNT protein antibody; ARNT_ antibody; Aryl hydrocarbon receptor nuclear translocator antibody; bHLHe2 antibody; Class E basic helix-loop-helix protein 2 antibody; Dioxin receptor antibody; Dioxin receptor nuclear translocator antibody; Drnt antibody; HIF 1 beta antibody; HIF 1beta antibody; HIF-1-beta antibody; HIF1-beta antibody; HIF1B antibody; HIF1beta antibody; Hypoxia Inducible Factor 1 antibody; Hypoxia inducible factor 1 beta antibody; Hypoxia-inducible factor 1-beta antibody; nuclear translocator antibody; Tango antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P27540 Immunogen:SyntheQuantityd peptide derived from internal of ARNT. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regµLator of the adaptive response to hypoxia. Hoffman E.C., Science 252:954-958(1991). Wang G.L., Proc. Natl. Acad. Sci. U.S.A. 92:5510-5514(1995). Nguyen T.A., Arch. Biochem. Biophys. 367:250-257(1999). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARNT Research Areas:Epigenetics and Nuclear Signaling;Cancer?CardiovascµLar;Metabolism