ELISA BAX anti-

Quantity :100µL Clone Number: Aliases:Apoptosis regµLator BAX antibody; BAX antibody; Bax-protein antibody; BAX_ antibody; BAXA antibody; Baxdelta2G9 antibody; Baxdelta2G9omega antibody; Baxdelta2omega antibody; Bcl-2-like protein 4 antibody; BCL2 associated X protein antibody; BCL2 associated X protein omega antibody; BCL2 associated X protein transcript variant delta2 antibody; Bcl2-L-4 antibody; BCL2L4 antibody; membrane isoform alpha antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q07812 Immunogen:SyntheQuantityd peptide derived from Bax. Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200 Background:Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. Francesca Andriani, J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324. H Martinez-Valdez, J. Exp. Med., Mar 1996; 183: 971. Joslyn K. Brunelle, J. Biol. Chem., Feb 2004; 279: 4305 - 4312. Renren Wen, Mol. Cell. Biol., Jan 2001; 21: 678 - 689. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BAX Research Areas:Cancer;Cell biology;Metabolism