ELISA CMKLR1 anti-

Quantity :100µL Clone Number: Aliases:CHEMERINR antibody; Chemokine like receptor 1 antibody; Chemokine-like receptor 1 antibody; CHEMR23 antibody; CMKLR1 antibody; CmL1_ antibody; DEZ antibody; G protein coupled receptor ChemR23 antibody; G protein coupled receptor DEZ antibody; G-protein coupled receptor ChemR23 antibody; G-protein coupled receptor DEZ antibody; Orphan G protein coupled receptor antibody; Orphan G protein coupled receptor Dez antibody; Resolvin E1 receptor antibody; RVER1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q99788 Immunogen:SyntheQuantityd peptide derived from internal of CMKLR1. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecµLe resolvin E1. Interaction with RARRES2 induces activation of intracellµLar signaling molecµLes, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to mµLtifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regµLates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regµLates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92µg024-2). Methner A., Biochem. Biophys. Res. Commun. 233:336-342(1997). Samson M., Eur. J. Immunol. 28:1689-1700(1998). Hillman R.T., Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CMKLR1 Research Areas:Cell biology;Signal transduction