ELISA BCL2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Apoptosis regµLator Bcl 2 antibody; Apoptosis regµLator Bcl-2 antibody; Apoptosis regµLator Bcl2 antibody; AW986256 antibody; B cell CLL/lymphoma 2 antibody; B cell leukemia/lymphoma 2 antibody; Bcl-2 antibody; Bcl2 antibody; BCL2_ antibody; C430015F12Rik antibody; D630044D05Rik antibody; D830018M01Rik antibody; Leukemia/lymphoma; B-cell; 2 antibody; Oncogene B-cell leukemia 2 antibody; PPP1R50 antibody; Protein phosphatase 1 regµLatory subunit 50 antibody; Protein phosphatase 1; regµLatory subunit 50 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P10415 Immunogen:Recombinant Apoptosis regµLator Bcl-2 protein (31-80AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. RegµLates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release (PubMed:17418785). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BCL2 Research Areas:Cancer; Cell biology; Metabolism; Signal transduction