ELISA BCL2 (Ab-70) anti-

Quantity :100µL Clone Number: Aliases:Apoptosis regµLator Bcl 2 antibody; Apoptosis regµLator Bcl-2 antibody; Apoptosis regµLator Bcl2 antibody; AW986256 antibody; B cell CLL/lymphoma 2 antibody; B cell leukemia/lymphoma 2 antibody; Bcl-2 antibody; Bcl2 antibody; BCL2_ antibody; C430015F12Rik antibody; D630044D05Rik antibody; D830018M01Rik antibody; Leukemia/lymphoma; B-cell; 2 antibody; Oncogene B-cell leukemia 2 antibody; PPP1R50 antibody; Protein phosphatase 1 regµLatory subunit 50 antibody; Protein phosphatase 1; regµLatory subunit 50 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P10415 Immunogen:Peptide sequence around aa.68~72 (R-T-S-P-L) derived from BCL-2. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200 Background:BCL-2 encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thoµght to be the cause of follicµLar lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. MµLler IM, et al. (2005) Mol Pharmacol. Jin Z, Gao F,et al. J Biol Chem 2004 Sep 17; 279(38): 40209-19. Kumar Biswas S,et al. Mol Cancer Ther 2004 Mar; 3(3): 327-34. Huang ST,et al. (2002)FASEB J; 16(8): 825-32. Yamamoto K,et al. (1999) Mol Cell Biol; 19(12): 8469-78. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BCL2 Research Areas:Cancer;Cell biology;Metabolism;Signal transduction