ELISA DCC anti-
Quantity :100µL
Clone Number:
Aliases:Colorectal cancer related chromosome sequence 18 antibody; Colorectal cancer suppressor antibody; CRC 18 antibody; CRC18 antibody; CRCR 1 antibody; CRCR1 antibody; DCC antibody; DCC_ antibody; Deleted in colorectal cancer protein antibody; Deleted in colorectal carcinoma antibody; ImmunoglobµLin superfamily DCC subclass member 1 antibody; Netrin receptor DCC antibody; Tumor suppressor protein DCC antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P43146
Immunogen:SyntheQuantityd peptide derived from internal of DCC.
Raised in:Rabbit
Reactivity:, Mouse
Tested Applications:ELISA, IF; IF:1:100-1:500
Background:Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repµLsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Hedrick L., Genes Dev. 8:1174-1183(1994).
Cho K.R., Genomics 19:525-531(1994).
Sjoeblom T., Science 314:268-274(2006).
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjµgate:Non-conjµgated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:DCC
Research Areas:Epigenetics and Nuclear Signaling?Neuroscience?Cancer;Cell biology
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