ELISA DDIT4L anti-

Quantity :50µL Clone Number: Aliases:DDIT4L antibody; REDD2 antibody; RTP801LDNA damage-inducible transcript 4-like protein antibody; HIF-1 responsive protein RTP801-like antibody; Protein regµLated in development and DNA damage response 2 antibody; REDD-2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q96D03 Immunogen:Fusion protein of DDIT4L Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:REDD-2 (regµLated in development and DNA damage response 2), also designated Rtp801L or DDIT4L (DNA-damage-inducible transcript 4-like), is a 193 amino acid cytoplasmic protein belonging to the DDIT4 family and is predominantly expressed in skeletal muscle. Considered a stress-inducted protein, REDD-2 is a negative regµLator of the mTOR (mammalian target of rapamycin) pathway. mTOR is a serine/threonine kinase that plays an essential role in cell growth control and is an important regµLator of skeletal muscle Quantity. Highly expressed in atherosclerotic lesions and macrophages, REDD-2 mediates monocyte cell death throµgh reduction of Trx (thioredoxin-1) expression. REDD2 expression in macrophages increases oxidized LDL (oxLDL)-induced cell death, sµggesting that REDD2 may play a critical role in arterial pathology. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DDIT4L Research Areas:Cell biology