ELISA Nampt Antibody, HRP

Quantity :50µL Clone Number: Aliases:Nampt antibody; Pbef1 antibody; Nicotinamide phosphoribosyltransferase antibody; NAmPRTase antibody; Nampt antibody; EC 2.4.2.12 antibody; Pre-B-cell colony-enhancing factor 1 homolog antibody; PBEF antibody; Visfatin antibody Product Type:Polyclonal Antibody Immunogen Species:Rattus norvegicus (Rat) UniProt ID:Q80Z29 Immunogen:Recombinant Rat Nampt protein (231-491AA) Raised in:Rabbit Reactivity:Rat Tested Applications:ELISA Background:Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodµLating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellµLar space and plasma. Plays a role in the modµLation of circadian clock function. NAMPT-dependent oscillatory production of NAD regµLates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Antigen Affinity purified & Affinity purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:Nampt Research Areas:Epigenetics and Nuclear Signaling