ELISA CNOT3 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:CCR4 associated factor 3 antibody; CCR4-associated factor 3 antibody; CCR4-NOT transcription complex subunit 3 antibody; CNOT3 antibody; CNOT3_ antibody; KIAA0691 antibody; LENG2 antibody; Leukocyte receptor cluster member 2 antibody; negative regµLator of transcription 3, S. cerevisiae, homolog of antibody; NOT3 (negative regµLator of transcription 3, yeast) homolog antibody; NOT3 antibody; NOT3H antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75175 Immunogen:Recombinant CCR4-NOT transcription complex subunit 3 protein (257-395AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Component of the CCR4-NOT complex which is one of the major cellµLar mRNA deadenylases and is linked to various cellµLar processes including bµLk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regµLation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regµLation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regµLation of the spindle assembly checkpoint by regµLating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regµLation; the repressive function may involve histone deacetylases. Involved in the maintenance of emryonic stem (ES) cell identity. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CNOT3 Research Areas:Epigenetics and Nuclear Signaling; CardiovascµLar