ELISA CIDEA Antibody, Biotin

Quantity :50µg Clone Number: Aliases:CIDEACell death activator CIDE-A antibody; Cell death-inducing DFFA-like effector A antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O60543 Immunogen:Recombinant Cell death activator CIDE-A protein (1-51AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Acts as a CEBPB coactivator in mammary epithelial cells to control the expression of a subset of CEBPB downstream target genes, including ID2, IGF1, PRLR, SOCS1, SOCS3, XDH, but not casein. By interacting with CEBPB, strengthens the association of CEBPB with the XDH promoter, increases histone acetylation and dissociates HDAC1 from the promoter (By similarity). Binds to lipid droplets and regµLates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair and occurs at a lower rate than that promoted by CIDEC. When overexpressed, induces apoptosis. The physiological significance of its role in apoptosis is unclear. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CIDEA Research Areas:Epigenetics and Nuclear Signaling; Cancer; CardiovascµLar; Cell biology; Metabolism