ELISA BMP10 Antibody, HRP

Quantity :50µg Clone Number: Aliases:BMP-10 antibody; Bmp10 antibody; BMP10_ antibody; Bone morphogenetic protein 10 antibody; Bone morphogenetic protein 10 preproprotein antibody; MGC126783 antibody; OTTHUMP00000159973 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O95393 Immunogen:Recombinant Bone morphogenetic protein 10 protein (317-424AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regµLator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BMP10 Research Areas:CardiovascµLar; Signal transduction