ELISA Birc5 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Birc5 antibody; Api4 antibody; Iap4BacµLoviral IAP repeat-containing protein 5 antibody; Apoptosis inhibitor 4 antibody; Apoptosis inhibitor survivin antibody; TIAP antibody Product Type:Polyclonal Antibody Immunogen Species:Mus muscµLus (Mouse) UniProt ID:O70201 Immunogen:Recombinant Mouse BacµLoviral IAP repeat-containing protein 5 protein (1-140AA) Raised in:Rabbit Reactivity:Mouse Tested Applications:ELISA Background:MµLtitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. Component of a chromosome passage protein complex (CPC) which is essential for chromosome alignment and segregation during mitosis and cytokinesis. Acts as an important regµLator of the localization of this complex; directs CPC movement to different locations from the inner centromere during prometaphase to midbody during cytokinesis and participates in the organization of the center spindle by associating with polymerized microtubµLes. The complex with RAN plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecµLe TPX2 to microtubµLes. May counteract a defaµLt induction of apoptosis in G2/M phase. The acetylated form represses STAT3 transactivation of target gene promoters. May play a role in neoplasia. Inhibitor of CASP3 and CASP7. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:Birc5 Research Areas:Others