ELISA BCL2L1 Antibody, HRP

Quantity :50µg Clone Number: Aliases:Apoptosis regµLator Bcl X antibody; Apoptosis regµLator Bcl-X antibody; Apoptosis regµLator BclX antibody; B cell lymphoma 2 like antibody; B2CL1_ antibody; Bcl 2 like 1 protein antibody; Bcl X antibody; Bcl xL antibody; BCL XL/S antibody; Bcl xS antibody; Bcl-2-like protein 1 antibody; Bcl2 Like 1 antibody; Bcl2 related gene antibody; Bcl2-L-1 antibody; BCL2L antibody; Bcl2l1 antibody; BCLX antibody; BclXL antibody; BclXs antibody; DKFZp781P2092 antibody; PPP1R52 antibody; Protein phosphatase 1 regµLatory subunit 52 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q07817 Immunogen:Recombinant Bcl-2-like protein 1 protein (1-209AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regµLate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regµLator of G2 checkpoint and progression to cytokinesis during mitosis. Ref.17 Ref.19 Ref.20 Isoform Bcl-X(L) also regµLates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as Quantity and number of synaptic vesicle clusters. During synaptic stimµLation, increases ATP availability from mitochondria throµgh regµLation of mitochondrial membrane ATP synthase F1F0 activity and regµLates endocytic vesicle retrieval in hippocampal neurons throµgh association with DMN1L and stimµLation of its GTPase activity in synaptic vesicles. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BCL2L1 Research Areas:Cancer; Cell biology; Metabolism; Signal transduction