ELISA ASNA1 anti-

Quantity :50µL Clone Number: Aliases:ARSA 1 antibody; ARSA antibody; ArsA arsenite transporter ATP binding homolog 1 antibody; ArsA arsenite transporter; ATP binding; E. coli; homolog of; 1 antibody; ArsA arsenite transporter; ATP-binding; homolog 1 (bacterial) antibody; ARSA I antibody; ARSA-I antibody; ARSA1 antibody; ARSAI antibody; Arsenical pump driving ATPase antibody; Arsenical pump-driving ATPase antibody; Arsenical resistance ATPase antibody; Arsenite translocating ATPase antibody; Arsenite transporting ATPase antibody; Arsenite-stimµLated ATPase antibody; ASNA 1 antibody; ASNA I antibody; ASNA-I antibody; ASNA_ antibody; ASNA1 antibody; Asna1 protein antibody; ASNAI antibody; ATPase ASNA1 antibody; GET3 antibody; Golgi to ER traffic 3 homolog antibody; hARSA-I antibody; hASNA-I antibody; MGC3821 antibody; Transmembrane domain recognition complex 40 kDa ATPase subunit antibody; Transmembrane domain recognition complex; 40kDa antibody; TRC40 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O43681 Immunogen:Recombinant ATPase ASNA1 protein (1-348AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticµLum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticµLum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regµLated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly syntheQuantityd TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting (By similarity). May be involved in insµLin signaling. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ASNA1 Research Areas:Cell biology; Metabolism; Signal transduction