ELISA AHR Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Ah receptor antibody; AhR antibody; AHR_ antibody; Aromatic hydrocarbon receptor antibody; Aryl hydrocarbon receptor antibody; Aryl hydrocarbon receptor precursor antibody; bHLHe76 antibody; Class E basic helix loop helix protein 76 antibody; Class E basic helix-loop-helix protein 76 antibody; HGNC:348 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P35869 Immunogen:Recombinant Aryl hydrocarbon receptor protein (126-353AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of mµLtiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regµLation. Likely to play an important role in the development and maturation of many tissues. RegµLates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:AHR Research Areas:Epigenetics and Nuclear Signaling