ELISA MMP12 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:MMP12(Matrix metalloproteinase-12) is a 54 kDa proenzyme that is processed into a 45 kDa and then a 22 kDa active form(15723202). MMP9 and MMP12 promote intimal thickening by independent cleavage of N-cadherin, which elevates vascµLar smooth muscle cell proliferation via beta-catenin signalling. Its overexpression in myeloid lineage cells plays a key role in modµLating myelopoiesis, immune suppression, and lung tumorigenesis(PMID: 21378275).
Immunogen:matrix metallopeptidase 12(macrophage elastase)
Synonyms:HME, Macrophage elastase, Macrophage metalloelastase, Matrix metalloproteinase 12, ME, MME, MMP 12, MMP12
Observed MW:54 kDa, 45 kDa
Uniprot ID:P39900
Reactivity:, Mouse
Tested Application:ELISA, WB, IHC, IF
Recommended dilution:WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100
Gene ID:4321
Research Area:CardiovascµLar, Metabolism
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