ELISA DBI anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes diazepam binding inhibitor, a protein that is regµLated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modµLate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regµLation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. MµLtiple transcript variants encoding different isoforms have been described for this gene. Immunogen:diazepam binding inhibitor (GABA receptor modµLator, acyl-Coenzyme A binding protein) Synonyms:DBI, ACBD1, ACBP, CCK-RP, EP, acyl-CoA-binding protein Observed MW:12 kDa Uniprot ID:P07108 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 Gene ID:1622 Research Area:Metabolism