ELISA CRK anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase throµgh SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regµLator of transformation whereas the C-terminal SH3 domain functions as a negative regµLator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. Immunogen:v-crk sarcoma virus CT10 oncogene homolog (avian) Synonyms: Observed MW:37 kDa Uniprot ID:P46108 Reactivity:, Mouse Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 Gene ID:1398 Research Area:CardiovascµLar, Signal Transduction