ELISA CNOT2 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Component of the CCR4-NOT complex which is one of the major cellµLar mRNA deadenylases and is linked to various cellµLar processes including bµLk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regµLation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regµLation; the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem(ES) cell identity.
Immunogen:CCR4-NOT transcription complex, subunit 2
Synonyms:CDC36, NOT2
Observed MW:60 kDa
Uniprot ID:Q9NZN8
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:4848
Research Area:Epigenetics, Metabolism
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