ELISA CNGA3 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellµLar calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3(By similarity). Essential for the generation of light-evoked electrical responses in the red-, green-and blue sensitive cones.
Immunogen:cyclic nucleotide gated channel alpha 3
Synonyms:CNCG3
Observed MW:98 kDa
Uniprot ID:Q16281
Reactivity:
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:1261
Research Area:Neuroscience, Signal Transduction
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