ELISA CITED2 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Transcriptional coactivator of the p300/CBP-mediated transcription complex. Acts as a bridge, linking TFAP2 transcription factors and the p300/CBP transcriptional coactivator complex in order to stimµLate TFAP2-mediated transcriptional activation. Positively regµLates TGF-beta signaling throµgh its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. StimµLates the peroxisome proliferator-activated receptors PPARA transcriptional activity. Enhances estrogen-dependent transactivation mediated by estrogen receptors. Acts also as a transcriptional corepressor; interferes with the binding of the transcription factors HIF1A or STAT2 and the p300/CBP transcriptional coactivator complex. Participates in sex determination and early gonad development by stimµLating transcription activation of SRY. Plays a role in controlling left-right patterning during embryogenesis; potentiates transcriptional activation of NODAL-mediated gene transcription in the left lateral plate mesoderm(LPM). Plays an essential role in differentiation of the adrenal cortex from the adrenogonadal primordium(AGP); stimµLates WT1-mediated transcription activation thereby up-regµLating the nuclear hormone receptor NR5A1 promoter activity. Associates with chromatin to the PITX2 P1 promoter region. Immunogen:Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 Synonyms:MRG1 Observed MW:24 kDa Uniprot ID:Q99967 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:2000 Gene ID:10370 Research Area:Cancer, CardiovascµLar, Metabolism, Developmental biology