ELISA CHST14 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Catalyzes the transfer of sµLfate to position 4 of the N-acetylgalactosamine(GalNAc) residue of dermatan sµLfate. Plays a pivotal role in the formation of 4-0-sµLfated IdoA blocks in dermatan sµLfate. Transfers sµLfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid(IdoUA) at the C-3 hydroxyl. Transfers sµLfate more efficiently to GalNAc residues in-IdoUA-GalNAc-IdoUA-than in-GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desµLfated dermatan sµLfate. Addition of sµLfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. GlcUA to IdoUA. Appears to have an important role in the formation of the cerbellar neural network during postnatal brain development.
Immunogen:carbohydrate(N-acetylgalactosamine 4-0) sµLfotransferase 14
Synonyms:D4ST1
Observed MW:45-50 kDa
Uniprot ID:Q8NCH0
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC
Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200
Gene ID:113189
Research Area:Metabolism
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