ELISA CHRNA9 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Ionotropic receptor with a probable role in the modµLation of auditory stimµLi. Agonist binding induces a conformation change that leads to the opening of an ion-conducting channel across the plasma membrane(PubMed:11752216, PubMed:25282151). The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane(PubMed:11752216, PubMed:25282151). In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. May also regµLate keratinocyte adhesion(PubMed:11021840).
Immunogen:cholinergic receptor, nicotinic, alpha 9
Synonyms:NACHRA9
Observed MW:50-55 kDa
Uniprot ID:Q9µgM1
Reactivity:, Mouse
Tested Application:ELISA, WB
Recommended dilution:WB: 1:500-1:2000
Gene ID:55584
Research Area:Neuroscience
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